Sevilla 1-2 Granada
High-flying Sevilla suffered their first La Liga defeat of the season as relegation favourites Granada came from behind to win at the Ramon Sanchez Pizjuan.
Sevilla, fifth going into the match against rock-bottom Granada, had led through Manu's opener in the first minute.
The hosts then battered the spirited strugglers without managing to add to their lead but were stunned when Alexandre Geijo equalised 11 minutes from time before Moreno Mikel Rico struck a winner in the 90th minute.
Less than a minute had gone when in-form striker Manu showed his sharpness by giving the hosts the lead, finding time and space to stab home right-footed from inside the box.
The jubilant home support sought a quick second goal but had to remain patient as Granada, who pushed champions Barcelona all the way in a narrow 1-0 defeat last week, put up a fight.
Winger Piotr Trochowski sent a trademark effort over the bar from distance in the third minute and was also off target with a free-kick soon after.
The German remained in the thick of it and in the 11th minute did force a save from Roberto, driving an effort from 18 yards which the goalkeeper tipped around the post.
Granada striker Ikechukwu Uche headed over the bar in the 27th minute and seconds later Abel Gomez forced Javi Varas to tip over his well-struck free-kick.
The momentum continued in the second half as Trochowski saw a shot saved before Roberto again looked unbeatable in denying winger Jesus Navas.
Manu sent a header wide in the 59th minute as the onslaught intensified. Navas sent a header wide before Roberto denied both Manu and midfielder Ivan Rakitic.
Manu had another shot saved before a rare foray upfield saw Uche blast over from inside the box.
Trochowski saw yet another attempt dealt with by Roberto before Franco Jara produced a rare effort for the visitors.
And in the 79th minute the Rojiblancos were stunned when Granada levelled.
Odion Ighalo tried his luck with a left-footed shot which hit the bar and Geijo reacted quickest to head home the rebound and put his side level.
Sevilla were stunned but after Guilherme Siqueira shot over for Granada, had a succession of hopeful chances.
Their misery was complete in the 90th minute, however, as Nigerian Ighalo showed great awareness to nod the ball to Mikel Rico who fired home the winner and wheeled away in delight.